Cusco to Arequipa

Cusco to Arequipa

Cusco
Arequipa
Thu, Sep 24
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Cusco to Arequipa Destination Reviews

AJ
Anne J
When we booked it, it said it was a lie-flat bus. However, the seats didn’t go all the way flat, which was disappointing because that was the reason we booked it.
Cusco to Arequipa, Bus Lie-flat, Cruz del Sur, Sep 13, 2026
BH
Benjamin H
Operator didn’t have my booking and I had to pay again, hopefully get a refund.
Cusco to Arequipa, Bus AC Semi Sleeper, Transzela, Aug 10, 2026
PH
Paul H
Bus was really cold, no blankets or pillows. Busdriver was the worst driver ever so you couldn’t really sleep because you got constantly shaken through the bus.
Cusco to Arequipa, Bus Sleeper, Cruz del Sur, May 7, 2026
4.4
17 customer reviews
5
64%
4
12%
3
12%
2
12%
1
0%

Cusco to Arequipa Schedule

TypeOperatorClassDeparture TimeArrival TimePriceRating
Taxi
Daytrip private transfer with English speaking driver
Minivan 7pax
Any time
+8h 37m
$580.00
Flight
LATAM Airlines Group
Economy
04:15
08:30
$87.30
Flight
LATAM Airlines Group
Economy
05:00
12:00
$75.81
Flight
LATAM Airlines Group
Economy
05:55
10:10
$215.55
Flight
LATAM Airlines Group
Economy
06:40
11:00
$401.58
Flight
JetSmart
Economy
06:57
14:26
$52.12
Flight
Sky Airline
Economy
07:15
20:50
$86.74
Flight
JetSmart
Economy
07:32
12:17
$40.32
Flight
LATAM Airlines Group
Economy
07:50
09:00
$40.20
Flight
LATAM Airlines Group
Economy
08:30
13:15
$149.62
Flight
Sky Airline
Economy
08:50
14:15
$75.81
Flight
LATAM Airlines Group
Economy
09:45
08:30
$238.64
Flight
LATAM Airlines Group
Economy
10:05
18:35
$260.77
Flight
LATAM Airlines Group
Economy
10:40
15:35
$87.38
Flight
JetSmart
Economy
10:57
16:46
$41.50
Flight
LATAM Airlines Group
Economy
11:15
15:30
$86.15
Flight
JetSmart
Economy
11:32
21:01
$48.58
Flight
JetSmart
Economy
11:52
20:42
$37.96
Flight
Sky Airline
Economy
12:10
20:55
$83.85
Flight
JetSmart
Economy
12:27
20:41
$104.04

How to get from Cusco to Arequipa

Travelling between Cusco and Arequipa is possible by Flight, bus and taxi. Flight guarantees the fastest travel on this route. Flight is the slowest option.

The most expensive ticket will cost you USD 30.32 if you go by Bus; to keep it budget-friendly, opt for a bus which will set you back mere USD 26.99.

How long does it take to get from Cusco to Arequipa?

It can take you anywhere between 2 and 24 hours to travel between Cusco and Arequipa depending on the means of transport you choose.

Flight is the fastest way to travel between Cusco and Arequipa. Flight will bring you to your destination in 1h 5m. Flight does a much slower job and take about 23h 35m to reach Arequipa.

How much does it cost to get from Cusco to Arequipa?

Travelling between Cusco and Arequipa can be as cheap as USD 26.99 if you opt for a Turismo Mer bus and as expensive as USD 30.32 if you buy a Jean Buss Bus ticket.

Here is the list of how much you can expect to pay travelling by each means of transport available for this route.

How many trips per day are there between Cusco and Arequipa ?

  • 2 from Cusco to Arequipa starting from 20:30 Cusco until 20:45 Cusco

Check above for a bus, train, flight and ferry timetable from Cusco to Arequipa.

What mode of transportation is the best one for my route?

Flights

Flying is the fastest and often the most expensive way to travel from Cusco to Arequipa, but with a bit of luck you can score very good deals for as little as USD 152.21.

Things to remember: Note that some of the airlines may have restrictions on checked luggage weight or require paying extra for check-in, choosing seats or transportation of oversized luggage.

If opting for a flight, calculate the time you will spend getting to and from the airports as well as the waiting time before your flight, getting through immigration in case of an international flight and recovering your checked luggage.

In certain cases all these procedures can add no less than 5 hours to your total travel time.

Airlines flying between Cusco and Arequipa

JetSmart, JetSMART Airlines, LATAM Airlines Group, LATAM Airlines Group, Sky Airline, Sky Airline

Bus

Travelling from Cusco to Arequipa overland will inevitably take longer but in many cases it is the cheapest option if you opt for a bus.

Things to remember: For a more comfortable ride opt for a higher-class bus wherever possible. These buses usually have soft reclining seats and are equipped with air-conditioning and on-board toilets.

They often include water, snacks or a light lunch into your ticket price and make bathroom stops en-route.

Companies operating bus routes between Cusco and Arequipa

Jean Buss, Turismo Mer

Taxi

Some travellers consider taxi to be the most convenient form of overland transport thanks to flexible departure times, a possibility to choose the size of the car you need, and a hassle-free door-to-door service.

Things to remember: If you are planning to make detours during your trip, discuss it with your driver or service provider in advance as it may affect the price.

Companies offering charters between Cusco and Arequipa

Daytrip private transfer with English speaking driver

What is the most popular transport to get from Cusco to Arequipa?

There is a choice of transportation means any time of the day with Bus remaining the most popular option due to their reasonable pricing and comfort.

Out of 1000 travellers who bought tickets for this route

  • 89% opted for a bus
  • 11% decided to fly

Transportation from Cusco to Arequipa

Facts about the transport from Cusco to Arequipa

Cheapest Transport$28
Fastest Transport1h 5m
Earliest Departure7:02 AM
Latest Departure9:37 PM
Departures per day2
Distance504 kilometers
Transport CompaniesJean Buss, JetSmart, JetSMART Airlines, LATAM Airlines Group, LATAM Airlines Group, Sky Airline, Sky Airline, Turismo Mer