| Boston South Station | Buffalo Airport | 01:00 | 01:15 |
| Boston South Station | Cherry Hill Mall | 01:00 | 01:10 |
| Boston South Station | Syracuse Bus Station | 01:00 | 01:12 |
| Boston South Station | WDC Bethesda | 01:00 | 01:11 |
| Boston South Station | Buffalo Bus Station | 01:00 | 01:15 |
| Boston South Station | Rochester Bus Stop | 01:00 | 01:13 |
| Boston South Station | Niagara Falls | 01:00 | 01:16 |
| Boston South Station | PhiladelphiaSchuylkill and Walnut | 01:00 | 01:10 |
| Boston South Station | Binghamton | 01:00 | 01:09 |
| Boston South Station | Philadelphia | 01:00 | 01:07 |
| Boston South Station | PhiladelphiaSchuylkill and Walnut | 01:30 | 01:37 |
| Boston South Station | Philadelphia | 01:30 | 01:37 |
| Boston South Station | Baltimore Downtown Bus Station | 01:30 | 01:38 |
| Boston South Station | Richmond North McDonalds Mechanicsville Tpk | 01:30 | 01:44 |
| Boston South Station | Washington Union Station | 01:30 | 01:40 |
| Boston South Station | Richmond Richmond th St and Ambler | 01:30 | 01:42 |
| Boston South Station | Newark NJ | 02:15 | 02:21 |
| Boston South Station | Cortland City Office Building | 02:15 | 02:25 |
| Boston South Station | Washington Union Station | 02:15 | 02:27 |
| Boston South Station | Hartford Union Station | 02:15 | 02:16 |
| Boston South Station | Binghamton | 02:15 | 02:24 |
| Boston South Station | Philadelphia | 02:15 | 02:23 |
| Boston South Station | Baltimore Downtown Bus Station | 02:15 | 02:25 |
| Boston South Station | NY Port Authority Bus Station | 02:15 | 02:19 |
| Boston South Station | White Plains Bus Station | 05:00 | 05:04 |
| Boston South Station | Raleigh Bus Station | 06:00 | 06:15 |
| Boston South Station | Richmond Main St Station Plaza | 06:00 | 06:11 |
| Boston South Station | Camden Walter Rand Trans Center | 06:45 | 06:52 |
| Boston South Station | Cortland City Office Building | 07:00 | 07:12 |
| Boston South Station | Buffalo Bus Station | 07:00 | 07:10 |
| Boston South Station | Montreal Gare d autocars de Montreal | 07:00 | 07:07 |
| Boston South Station | Toronto Union Station Bus Terminal | 07:00 | 07:14 |
| Boston South Station | Binghamton | 07:00 | 07:08 |
| Boston South Station | Albany Bus Terminal NY | 07:00 | 07:03 |
| Boston South Station | Niagara Falls | 07:00 | 07:12 |
| Boston South Station | Syracuse Bus Station | 07:00 | 07:06 |
| Boston South Station | Rochester Bus Stop | 07:00 | 07:08 |
| Boston South Station | Utica Bus Stop | 07:00 | 07:05 |
| Boston South Station | Hartford Union Station | 07:00 | 07:03 |
| Boston South Station | Buffalo Airport | 07:00 | 07:11 |
| Boston South Station | Providence Convention Center | 07:15 | 07:16 |
| Boston South Station | Baltimore Downtown Bus Station | 07:20 | 07:28 |
| Boston South Station | PhiladelphiaSchuylkill and Walnut | 07:20 | 07:27 |
| Boston South Station | Baltimore Downtown Bus Station | 08:00 | 08:08 |
| Boston South Station | Ithaca | 08:00 | 08:10 |
| Boston South Station | Washington Union Station | 08:00 | 08:09 |
| Boston South Station | Providence Convention Center | 08:10 | 08:11 |
| Boston South Station | Queens Village 7 11 | 08:10 | 08:17 |
| Boston South Station | Detroit Bus Station | 08:10 | 08:35 |
| Boston South Station | PhiladelphiaSchuylkill and Walnut | 08:10 | 08:18 |
| Boston South Station | Syracuse Bus Station | 08:55 | 09:05 |
| Boston South Station | Newark NJ | 08:55 | 09:00 |
| Boston South Station | Cleveland Downtown E 12th St | 08:55 | 09:14 |
| Boston South Station | Washington Union Station | 08:55 | 09:05 |
| Boston South Station | Binghamton | 08:55 | 09:04 |
| Boston South Station | NY GW Bridge Bus Stop | 08:55 | 08:59 |
| Boston South Station | Arlington Rosslyn | 08:55 | 09:05 |
| Boston South Station | Philadelphia | 08:55 | 09:02 |
| Boston South Station | Baltimore Downtown Bus Station | 09:00 | 09:09 |
| Boston South Station | WDC Bethesda | 09:00 | 09:10 |
| Boston South Station | NYC Lucky Star 145 Canal | 10:00 | 10:05 |
| Boston South Station | Richmond Willow Lawn Dr | 10:15 | 10:27 |
| Boston South Station | Cortland Onvo Travel Plaza | 10:15 | 10:25 |
| Boston South Station | Philadelphia | 10:30 | 10:38 |
| Boston South Station | Springfield Union Station | 10:30 | 10:32 |
| Boston South Station | New York W 34th St 12th Ave | 10:30 | 10:36 |
| Boston South Station | Springfield Union Station | 10:45 | 10:46 |
| Boston South Station | Philadelphia | 10:45 | 10:53 |
| Boston South Station | New Haven Union Av | 10:45 | 10:48 |
| Boston South Station | Newark NJ | 10:45 | 10:51 |
| Boston South Station | Queens Jamaica | 11:00 | 11:04 |
| Boston South Station | New Haven Bus Stop | 11:10 | 11:16 |
| Boston South Station | Syracuse Bus Station | 11:15 | 11:26 |
| Boston South Station | Malvern | 12:15 | 12:23 |
| Boston South Station | Washington Union Station | 12:45 | 12:55 |
| Boston South Station | Hartford Union Station | 12:45 | 12:46 |
| Boston South Station | Concord Concord Coach Lines | 13:00 | 13:01 |
| Boston South Station | Manchesterveterans Memorial Park | 13:00 | 13:01 |
| Boston South Station | Boston Manchester Airport | 13:00 | 13:01 |
| Boston South Station | Binghamton | 13:15 | 13:25 |
| Boston South Station | Washington Union Station | 13:15 | 13:25 |
| Boston South Station | Baltimore Downtown Bus Station | 13:15 | 13:24 |
| Boston South Station | NY W 31st St Bus Stop | 13:15 | 13:19 |
| Boston South Station | PhiladelphiaSchuylkill and Walnut | 13:15 | 13:22 |
| Boston South Station | New Haven Bus Stop | 14:15 | 14:18 |
| Boston South Station | New Haven Union Av | 15:00 | 15:02 |
| Boston South Station | Worcester Union Station | 15:00 | 15:01 |
| Boston South Station | Dc Dupont Circle | 15:00 | 15:10 |
| Boston South Station | New Haven Bus Stop | 15:05 | 15:09 |
| Boston South Station | Niagara Falls Niagara River Parkway | 15:05 | 15:18 |
| Boston South Station | Raleigh Bus Station | 15:05 | 15:20 |
| Boston South Station | Richmond Main St Station Plaza | 15:05 | 15:17 |
| Boston South Station | Toronto Union Station Bus Terminal | 15:05 | 15:20 |
| Boston South Station | Scarborough | 15:05 | 15:21 |
| Boston South Station | Washington Union Station | 15:05 | 15:15 |
| Boston South Station | Ithaca | 16:15 | 16:23 |
| Boston South Station | Buffalo Bus Station | 16:15 | 16:27 |
| Boston South Station | Niagara Falls | 16:15 | 16:29 |
| Boston South Station | Niagara Falls Niagara River Parkway | 16:15 | 16:29 |
| Boston South Station | Queens Flushing | 16:15 | 16:19 |