Manizales
| Origin | Destination | Departure | Arrival |
| Manizales | Medellin | 04:00 | 04:05 |
| Manizales | Medellin | 04:30 | 04:34 |
| Manizales | Medellin | 05:00 | 05:05 |
| Manizales | Palmira | 05:15 | 05:19 |
| Manizales | Cali | 05:15 | 05:20 |
| Manizales | Calarca | 06:30 | 06:33 |
| Manizales | Armenia | 06:30 | 06:33 |
| Manizales | Pereira | 06:30 | 06:31 |
| Manizales | Pereira | 08:00 | 08:01 |
| Manizales | Medellin | 08:30 | 08:34 |
| Manizales | Cali | 12:30 | 12:34 |
| Manizales | Pereira | 12:30 | 12:31 |
| Manizales | Pereira | 13:00 | 13:01 |
| Manizales | Pereira | 14:35 | 14:36 |
| Manizales | Bogota | 19:00 | 19:09 |
| Manizales | Pereira | 19:00 | 19:01 |
| Manizales | Pereira | 19:30 | 19:32 |
| Manizales | Bogota | 22:00 | 22:08 |
| Manizales | Bogota | 22:00 | 22:08 |
| Manizales | Bogota | 22:00 | 22:08 |
| Type | Name | km |
| bus | Terminal de Transportes de Manizales | 0.0 |
| bus | Manizales Bus Station | 0.2 |
| van | Manizales Transfer | 1.6 |
| van | Manizales La Nubia Airport | 4.7 |
| avia | Manizales Airport | 5.1 |